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Who is MR. SA . . .what you need to know about Methicillin-Resistant Staph aureus

Media coverage of Methicillin-resistant Staphylococcus aureus, or MRSA (pronounced Mursa or Mr. SA) splashes the newspapers and is a buzzword on network news.  But, what is MRSA, and how do you get MRSA? MRSA is a bacterium which causes Staph infections.  There are 2 types of MRSA, community -acquired MRSA and hospital-acquired MRSA.  The community -acquired MRSA, CA-MRSA, has been traced to gymnasiums, workplaces, ambulances, police cars, artificial turf, and sports equipment.  Hospital-aquired MRSA, or HA-MRSA, is transmitted at hospitals. 

Treatments for community environments include topical sanitizing by alcohol and chlorine bleach and can be used in combination with quaternary ammonium to increase the effective sanitized time.  Sporting goods can be effectively sanitized by ozone gas, and should be thoroughly cleaned regularly to prevent cross-contamination.

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The US Centers for Disease Control and Prevention provides "Guidelines for Infection Control in Health Care Personnel" to prevent the spread of MRSA in health care workers.  There are no requirements that workers with MRSA in non-healthcare settings should be excluded from work.  Employers should provide and encourage good personal hygiene to prevent an outbreak.

An early indication of MRSA is a spider-bite like wound.  Symptoms of MRSA are pus filled boils and sometimes rashes.  Testing for MRSA includes isolation of the bacterium from nostril swabs.  Immunocompromised individuals such as recent surgery patients, AIDS patients, cancer patients, and people with open wounds are at an increased risk of infection.  However, there have been reports of infection among healthy athletes.

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There are a limited number of treatments for this type of infection.  The strains of this bacterium are resistant and change often which can prevent use of common antibiotics.   Drugs available for treatment of MRSA are vancomycin, teicoplanin, and glycopeptide antibiotics.  A second tier set of prescriptions includes linezloid, quinupristin/dalfopristin, daptomycin, and tigecycline, rifampicin+fusidic acid, doxicycline, minocycline, and clindamycin.  Some of the treatments are administered orally, others intraveinously.  A last resort treatment for MRSA is maggot therapy.  Phage therapy is also a promising treatment for MRSA and is still in a research phase. 

The best practices for prevention of MRSA are good personal hygiene, proper sanitation of surfaces, and regular cleaning of sporting goods.